| | |  | | | | Record from Web of Science® | | | | | | |
| Hamartomatous polyps of the colon - Ganglioneuromatous, stromal, and lipomatous |
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| Author(s): Chan OTM (Chan, Owen T. M.), Haghighi P (Haghighi, Parviz) |
| Source: ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE Volume: 130 Issue: 10 Pages: 1561-1566 Published: OCT 2006 |
| Times Cited: 8 References: 47 |
| Abstract: Intestinal ganglioneuromas comprise benign, hamartomatous polyps characterized by an overgrowth of nerve ganglion cells, nerve fibers, and supporting cells in the gastrointestinal tract. This polyposis has been divided into 3 subgroups, each with a different degree of ganglioneuroma formation: polypoid ganglioneuroma, ganglioneuromatous polyposis, and diffuse ganglioneuromatosis. The ganglioneuromatous polyposis subgroup is not known to coexist with systemic disorders that often have an associated intestinal polyposis, such as multiple endocrine neoplasia type IIb, neurofibromatosis type 1, and Cowden syndrome. We report a case of ganglioneuromatous polyposis plus cutaneous lipomatosis in a 41-year-old man with no established systemic disease. However, he possessed unique anatomic findings in addition to his ganglioneuromatosis, suggesting that the ganglioneuromatosis-lipomatosis in our patient may represent an unrecognized syndrome. This case report and brief review of the literature provide an overview of intestinal ganglioneuromatosis in relation to the hereditary polyposis syndromes and describe the individual ganglioneuromatosis subgroups. |
| Document Type: Article |
| Language: English |
| Reprint Address: Chan, OTM (reprint author), VA Med Ctr, 3350 La Jolla Village Dr, San Diego, CA 92161 USA |
Addresses:
1. VA Med Ctr, San Diego, CA 92161 USA
2. Univ Calif San Diego, Dept Pathol, San Diego, CA 92103 USA |
| Publisher: COLLEGE AMER PATHOLOGISTS, C/O KIMBERLY GACKI, 325 WAUKEGAN RD, NORTHFIELD, IL 60093-2750 USA |
| Subject Category: Medical Laboratory Technology; Medicine, Research & Experimental; Pathology |
| IDS Number: 091SS |
| ISSN: 0003-9985 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |