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Abdominal obesity and metabolic syndrome
Author(s): Despres JP (Despres, Jean-Pierre), Lemieux I (Lemieux, Isabelle)
Source: NATURE    Volume: 444    Issue: 7121    Pages: 881-887    Published: DEC 14 2006  
Times Cited: 329     References: 94     
Abstract: Metabolic syndrome is associated with abdominal obesity, blood lipid disorders, inflammation, insulin resistance or full-blown diabetes, and increased risk of developing cardiovascular disease. Proposed criteria for identifying patients with metabolic syndrome have contributed greatly to preventive medicine, but the value of metabolic syndrome as a scientific concept remains controversial. The presence of metabolic syndrome alone cannot predict global cardiovascular disease risk. But abdominal obesity - the most prevalent manifestation of metabolic syndrome - is a marker of 'dysfunctional adipose tissue', and is of central importance in clinical diagnosis. Better risk assessment algorithms are needed to quantify diabetes and cardiovascular disease risk on a global scale.
Document Type: Article
Language: English
Reprint Address: Despres, JP (reprint author), Hop Laval, Res Ctr, Quebec Heart Inst, 2725 Chemin St Foy,Pavil Marguerite DYouville,4t, Ste Foy, PQ G1V 4G5 Canada
Addresses:
1. Hop Laval, Res Ctr, Quebec Heart Inst, Ste Foy, PQ G1V 4G5 Canada
2. Univ Laval, Dept Social & Prevent Med, Div Kinesiol, Quebec City, PQ G1K 7P4 Canada
Publisher: NATURE PUBLISHING GROUP, MACMILLAN BUILDING, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
Subject Category: Multidisciplinary Sciences
IDS Number: 116LW
ISSN: 0028-0836
DOI: 10.1038/nature05488
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