| | |  | | | | Record from Web of Science® | | | | | | |
| Technology Insight: can neuroimaging provide insights into the role of ischemia in Balo's concentric sclerosis? |
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| Author(s): Mowry EM (Mowry, Ellen M.), Woo JH (Woo, John H.), Ances BM (Ances, Beau M.) |
| Source: NATURE CLINICAL PRACTICE NEUROLOGY Volume: 3 Issue: 6 Pages: 341-348 Published: JUN 2007 |
| Times Cited: 3 References: 55 |
| Abstract: Balo's concentric sclerosis (BCS) has long been considered to be a variant of multiple sclerosis. Although BCS was initially described over 100 years ago, relatively few antemortem cases have been identified, and the exact pathogenesis remains unknown. Inflammatory protective ischemic preconditioning has recently been suggested as a mechanism by which the typical concentric rings of the BCS lesion are formed. Advanced neuroimaging can provide important in vivo markers of disease progression that can assist in the diagnosis and management of patients with BCS. In this Review, we discuss evidence from longitudinal neuroimaging studies that supports the role of ischemic preconditioning in BCS. |
| Document Type: Review |
| Language: English |
| Reprint Address: Ances, BM (reprint author), HIV Neurobehav Res Ctr, 150 W Washington St,2nd Floor, San Diego, CA 92103 USA |
Addresses:
1. Univ Penn, Dept Neurol, Philadelphia, PA 19104 USA
2. Univ Penn, Dept Radiol, Philadelphia, PA 19104 USA
3. Univ Calif San Diego, Dept Neurosci, San Diego, CA 92103 USA
4. Univ Calif San Diego, Dept Radiol, San Diego, CA 92103 USA |
| Publisher: NATURE PUBLISHING GROUP, 75 VARICK STREET, 9TH FLOOR, NEW YORK, NY 10013-1917 USA |
| Subject Category: Clinical Neurology |
| IDS Number: 175QV |
| ISSN: 1745-834X |
| DOI: 10.1038/ncpneuro0519 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |