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| THE GTPASE SUPERFAMILY - CONSERVED STRUCTURE AND MOLECULAR MECHANISM |
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| Author(s): BOURNE HR, SANDERS DA, MCCORMICK F |
| Source: NATURE Volume: 349 Issue: 6305 Pages: 117-127 Published: JAN 10 1991 |
| Times Cited: 2,325 References: 150 |
| Abstract: GTPases are conserved molecular switches, built according to a common structural design. Rapidly accruing knowledge of individual GTPases - crystal structures, biochemical properties, or results of molecular genetic experiments - support and generate hypotheses relating structure to function in other members of the diverse family of GTPases. |
| Document Type: Review |
| Language: English |
| Reprint Address: BOURNE, HR (reprint author), UNIV CALIF SAN FRANCISCO, DEPT PHARMACOL, SAN FRANCISCO, CA 94110 USA |
Addresses:
1. UNIV CALIF SAN FRANCISCO, DEPT MED, SAN FRANCISCO, CA 94110 USA 2. UNIV CALIF SAN FRANCISCO, CARDIOVASC RES INST, SAN FRANCISCO, CA 94110 USA 3. CETUS CORP, DEPT MOLEC BIOL, EMERYVILLE, CA 94608 USA |
| Publisher: MACMILLAN MAGAZINES LTD, 4 LITTLE ESSEX STREET, LONDON, ENGLAND WC2R 3LF |
| Subject Category: Multidisciplinary Sciences |
| IDS Number: ER418 |
| ISSN: 0028-0836 |
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| |  |  |  |  | | | | Record from Web of Science® | |  |  | | | | | | |