| | |  | | | | Record from Web of Science® | |  |  | | |  |
| GENETIC-ASPECTS OF ANTIBIOTIC INDUCED DEAFNESS - MITOCHONDRIAL INHERITANCE |
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| Author(s): HU DN, QIU WQ, WU BT, FANG LZ, ZHOU F, GU YP, ZHANG QH, YAN JH, DING YQ, WONG H |
| Source: JOURNAL OF MEDICAL GENETICS Volume: 28 Issue: 2 Pages: 79-83 Published: FEB 1991 |
| Times Cited: 82 References: 24 |
| Abstract: Analysis of 36 pedigrees with a positive family history of aminoglycoside antibiotic induced deafness, ascertained in a population of 483 611 in Zhabei District in Shanghai, showed that the susceptibility to antibiotic ototoxicity was transmitted by females exclusively, indicating mitochondrial inheritance. Reanalysis of 18 other published pedigrees confirmed this conclusion. |
| Document Type: Article |
| Language: English |
Addresses:
1. TIEDAO MED COLL, NATL CTR GENET MED, DEPT GENET COUNSELLING, SHANGHAI, PEOPLES R CHINA 2. ZHABEI EYE HOSP, DEPT POPULAT GENET, SHANGHAI, PEOPLES R CHINA 3. ZHABEI CENT HOSP, DEPT OTORHINOLARYNGOL, SHANGHAI, PEOPLES R CHINA 4. TIEDAO MED COLL, DEPT MED GENET, SHANGHAI, PEOPLES R CHINA |
| Publisher: BRITISH MED JOURNAL PUBL GROUP, BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON, ENGLAND WC1H 9JR |
| Subject Category: Genetics & Heredity |
| IDS Number: ET757 |
| ISSN: 0022-2593 |
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| |  |  |  |  | | | | Record from Web of Science® | |  |  | | | | | | |