| | |  | | | | Record from Web of Science® | | | | | | |
| SEQUENCE AND EXPRESSION OF A METABOTROPIC GLUTAMATE RECEPTOR |
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| Author(s): MASU M, TANABE Y, TSUCHIDA K, SHIGEMOTO R, NAKANISHI S |
| Source: NATURE Volume: 349 Issue: 6312 Pages: 760-765 Published: FEB 28 1991 |
| Times Cited: 944 References: 36 |
| Abstract: The complementary DNA of a metabotropic glutamate receptor coupled to inositol phosphate/Ca2+ signal transduction has been cloned and characterized. This receptor shows no sequence similarity to conventional G protein-coupled receptors and has a unique structure with large hydrophilic sequences at both sides of seven putative membrane-spanning domains. Abundant expression of this messenger RNA is observed in neuronal cells in hippocampal dentate gyrus and CA2-3 and in cerebellar Purkinje cells, suggesting the importance of this receptor in specific hippocampal and cerebellar functions. |
| Document Type: Article |
| Language: English |
Addresses:
1. KYOTO UNIV, FAC MED, INST IMMUNOL, KYOTO 606, JAPAN
2. KYOTO UNIV, FAC MED, DEPT MORPHOL BRAIN SCI, KYOTO 606, JAPAN |
| Publisher: MACMILLAN MAGAZINES LTD, 4 LITTLE ESSEX STREET, LONDON, ENGLAND WC2R 3LF |
| Subject Category: Multidisciplinary Sciences |
| IDS Number: EZ666 |
| ISSN: 0028-0836 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |