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| FLUORESCENCE INSITU HYBRIDIZATION - APPLICATIONS IN CYTOGENETICS AND GENE-MAPPING |
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| Author(s): TRASK BJ |
| Source: TRENDS IN GENETICS Volume: 7 Issue: 5 Pages: 149-154 Published: MAY 1991 |
| Times Cited: 306 References: 41 |
| Abstract: Unique sequences, chromosomal subregions, or entire genomes can be specifically highlighted in metaphase or interphase cells by fluorescence in situ hybridization (FISH). This technique can be used to identify chromosomes, detect chromosomal abnormalities or determine the chromosomal location of specific sequences. FISH plays an increasingly important role in a variety of research areas, including cytogenetics, prenatal diagnosis, tumor biology, gene amplification and gene mapping. |
| Document Type: Article |
| Language: English |
| Reprint Address: TRASK, BJ (reprint author), UNIV CALIF LAWRENCE LIVERMORE NATL LAB, DIV BIOMED SCI, LIVERMORE, CA 94550 USA |
| Publisher: ELSEVIER SCI LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, OXON, ENGLAND OX5 1GB |
| Subject Category: Genetics & Heredity |
| IDS Number: FJ476 |
| ISSN: 0168-9525 |
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| |  |  |  |  | | | | Record from Web of Science® | |  |  | | | | | | |