| | |  | | | | Record from Web of Science® | | | | | | |
| ALLELE-SPECIFIC MOTIFS REVEALED BY SEQUENCING OF SELF-PEPTIDES ELUTED FROM MHC MOLECULES |
|
|
| Author(s): FALK K, ROTZSCHKE O, STEVANOVIC S, JUNG G, RAMMENSEE HG |
| Source: NATURE Volume: 351 Issue: 6324 Pages: 290-296 Published: MAY 23 1991 |
| Times Cited: 1,895 References: 47 |
| Abstract: The crystal structures of major histocompatibility complex (MHC) molecules contain a groove occupied by heterogeneous material thought to represent peptides central to immune recognition, although until now relatively little characterization of the peptides has been possible. Exact information about the contents of MHC grooves is now provided. Moreover, each MHC class I allele has its individual rules to which peptides presented in the grove adhere. |
| Document Type: Article |
| Language: English |
| Reprint Address: RAMMENSEE, HG (reprint author), MAX PLANCK INST BIOL, IMMUNOGENET ABT, CORRENSSTR 42, W-7400 TUBINGEN, GERMANY |
Addresses:
1. UNIV TUBINGEN, INST ORGAN CHEM, W-7400 TUBINGEN 1, GERMANY |
| Publisher: MACMILLAN MAGAZINES LTD, 4 LITTLE ESSEX STREET, LONDON, ENGLAND WC2R 3LF |
| Subject Category: Multidisciplinary Sciences |
| IDS Number: FM976 |
| ISSN: 0028-0836 |
|
| | | | | | | | | Record from Web of Science® | | | | | | | | | |