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| HOX GENE ACTIVATION BY RETINOIC ACID |
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| Author(s): BONCINELLI E, SIMEONE A, ACAMPORA D, MAVILIO F |
| Source: TRENDS IN GENETICS Volume: 7 Issue: 10 Pages: 329-334 Published: OCT 1991 |
| Times Cited: 172 References: 38 |
| Abstract: Vertebrate homeobox genes of the Hox family are, like Drosophila homeotic genes, organized in gene clusters and show a strict correspondence, or collinearity, between the order of the genes (3' to 5') within the chromosomal cluster and that of their expression domains (anterior to posterior) in the embryo. Recent data obtained from embryonal carcinoma cells induced to differentiate by retinoic acid cast some light on the molecular mechanisms underlying the collinear expression of the Hox genes. |
| Document Type: Review |
| Language: English |
| Reprint Address: BONCINELLI, E (reprint author), CNR, INT INST GENET & BIOPHYS, VIA MARCONI 10, I-80125 NAPLES, ITALY |
Addresses:
1. IST SCI HS RAFFAELE, I-20132 MILAN, ITALY |
| Publisher: ELSEVIER SCI LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, OXON, ENGLAND OX5 1GB |
| Subject Category: Genetics & Heredity |
| IDS Number: GG258 |
| ISSN: 0168-9525 |
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| |  |  |  |  | | | | Record from Web of Science® | |  |  | | | | | | |