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| PSORIASIS INDUCED BY INTERFERON-ALPHA |
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| Author(s): FUNK J, LANGELAND T, SCHRUMPF E, HANSSEN LE |
| Source: BRITISH JOURNAL OF DERMATOLOGY Volume: 125 Issue: 5 Pages: 463-465 Published: NOV 1991 |
| Times Cited: 85 References: 21 |
| Abstract: Recombinant human interferon-alpha has been used in the treatment of several cancers, but there have been several reports that it may exacerbate psoriasis or trigger off its onset. We report four patients, three of whom first developed psoriasis and one who had an aggravation of the condition during treatment with interferon-alpha. Three of the patients had the carcinoid syndrome and one a renal carcinoma, and all were treated with interferon-alpha-2b or 2a (IFN-alpha-2b, 2a) with doses ranging from 1.5 x 1O(6) U daily to 18 x 10(6) U three times weekly. In two of the patients there appeared to be a correlation between the severity of the psoriasis and the dosage of interferon. |
| Document Type: Article |
| Language: English |
| Reprint Address: FUNK, J (reprint author), NATL HOSP NORWAY, DEPT DERMATOL, PILESTREDT 32, N-0027 OSLO 1, NORWAY |
Addresses:
1. NATL HOSP NORWAY, DEPT INTERNAL MED, OSLO 1, NORWAY |
| Publisher: BLACKWELL SCIENCE LTD, OSNEY MEAD, OXFORD, OXON, ENGLAND OX2 0EL |
| Subject Category: Dermatology |
| IDS Number: GN770 |
| ISSN: 0007-0963 |
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