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INVOLVEMENT OF MIXED-FUNCTION OXIDASE SYSTEMS IN POLYCHLORINATED BIPHENYL METABOLISM BY PLANT-CELLS
Author(s): LEE I, FLETCHER JS
Source: PLANT CELL REPORTS    Volume: 11    Issue: 2    Pages: 97-100    Published: MAR 1992  
Times Cited: 19     References: 17     
Abstract: Nineteen different polychlorinated biphenyl (PCB) congeners ranging in chlorine content from 2 to 6 chlorine atoms were provided to nonphotosynthetic suspension cultures of rose (Rosa sp. cv. Paul's Scarlet). After a 96 h incubation period, 11 individual congeners had been metabolized by > 10%. Provision of mixed function oxidase inhibitors (10 mM metyrapone or 0.5 mM 7,8-benzoflavone) either stopped or severely reduced the metabolism of individual congeners; whereas (inhibitors of peroxidase) (1 mM benzoate or 1 mM n-propylgallate) had minimal influence on PCB metabolism. The metabolism of PCBs by rose cultures appears to be catalyzed by a cytochrome P-450-and/or P-448-dependent enzyme system.
Document Type: Article
Language: English
Addresses:
1. UNIV OKLAHOMA, DEPT BOT & MICROBIOL, NORMAN, OK 73019 USA
Publisher: SPRINGER VERLAG, 175 FIFTH AVE, NEW YORK, NY 10010
Subject Category: Plant Sciences
IDS Number: HL036
ISSN: 0721-7714
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