| | |  | | | | Record from Web of Science® | | | | | | |
| A GENETIC-MAP OF THE MOUSE SUITABLE FOR TYPING INTRASPECIFIC CROSSES |
|
|
| Author(s): DIETRICH W, KATZ H, LINCOLN SE, SHIN HS, FRIEDMAN J, DRACOPOLI NC, LANDER ES |
| Source: GENETICS Volume: 131 Issue: 2 Pages: 423-447 Published: JUN 1992 |
| Times Cited: 1,067 References: 60 |
| Abstract: We report the construction of a genetic linkage map of the mouse, consisting entirely of genetic markers that can be rapidly typed by polymerase chain reaction and that show a high degree of polymorphism among inbred laboratory strains. Specifically, the map contains 317 simple sequence length polymorphisms at an average spacing of 4.3 cM and is detectably linked to approximately 99% of the mouse genome. In typical crosses between inbred laboratory strains, about 50% of the markers are polymorphic, making it straightforward to follow inheritance in almost any cross. |
| Document Type: Article |
| Language: English |
| Reprint Address: DIETRICH, W (reprint author), WHITEHEAD INST BIOMED RES, CAMBRIDGE, MA 02142 USA |
Addresses:
1. MIT, CTR GENOME RES, CAMBRIDGE, MA 02139 USA
2. MIT, DEPT BIOL, CAMBRIDGE, MA 02139 USA
3. ROCKEFELLER UNIV, NEW YORK, NY 10021 USA |
| Publisher: GENETICS, 428 EAST PRESTON ST, BALTIMORE, MD 21202 |
| Subject Category: Genetics & Heredity |
| IDS Number: HW759 |
| ISSN: 0016-6731 |
|
| | | | | | | | | Record from Web of Science® | | | | | | | | | |