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| PROGNOSTIC FACTORS FOR LOCAL RECURRENCE, METASTASIS, AND SURVIVAL RATES IN SQUAMOUS-CELL CARCINOMA OF THE SKIN, EAR, AND LIP - IMPLICATIONS FOR TREATMENT MODALITY SELECTION |
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| Author(s): ROWE DE, CARROLL RJ, DAY CL |
| Source: JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY Volume: 26 Issue: 6 Pages: 976-990 Published: JUN 1992 |
| Times Cited: 313 References: 229 |
| Abstract: We reviewed all studies since 1940 on the prognosis of squamous cell carcinoma (SCC) of the skin and lip. The following variables are correlated with local recurrence and metastatic rates: (1) treatment modality, (2) prior treatment, (3) location, (4) size, (5) depth, (6) histologic differentiation, (7) histologic evidence of perineural involvement, (8) precipitating factors other than ultraviolet light, and (9) host immunosuppression. Local recurrences occur less frequently when SCC is treated by Mohs micrographic surgery. This local recurrence rate differential in favor of Mohs micrographic surgery holds true for primary SCC of the skin and lip (3.1% vs 10.9%), for ear SCC (5.3% vs 18.7%), for locally recurrent (previously treated) SCC (10% vs 23.3%), for SCC with perineural involvement (0% vs 47%), for SCC of size greater than 2 cm (25.2% vs 41.7%), and for SCC that is poorly differentiated (32.6% vs 53.6%). |
| Document Type: Review |
| Language: English |
Addresses:
1. UNIV TEXAS, HLTH SCI CTR, SAN ANTONIO, TX 78284 USA
2. TEXAS A&M UNIV SYST, COLLEGE STN, TX 77843 USA
3. UNIV CALIF LOS ANGELES, LOS ANGELES, CA 90024 USA |
| Publisher: MOSBY-YEAR BOOK INC, 11830 WESTLINE INDUSTRIAL DR, ST LOUIS, MO 63146-3318 |
| Subject Category: Dermatology |
| IDS Number: HW817 |
| ISSN: 0190-9622 |
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