| | |  | | | | Record from Web of Science® | | | | | | |
| THE ORIGIN AND FUNCTION OF TUMOR-ASSOCIATED MACROPHAGES |
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| Author(s): MANTOVANI A, BOTTAZZI B, COLOTTA F, SOZZANI S, RUCO L |
| Source: IMMUNOLOGY TODAY Volume: 13 Issue: 7 Pages: 265-270 Published: JUL 1992 |
| Times Cited: 571 References: 66 |
| Abstract: Tumor-associated macrophages (TAM) hate a complex relationship with the neoplastic cells of the tumor. On the one hand, the two cell types produce reciprocal growth factors and may be considered to have a symbiotic relationship. On the other hand, TAM can be activated to inhibit tumor growth and destroy neoplastic cells. Here, Alberto Mantovani and colleagues describe this delicate balance and the prospects for its therapeutic manipulation. |
| Document Type: Review |
| Language: English |
| Reprint Address: MANTOVANI, A (reprint author), MARIO NEGRI INST PHARMACOL RES, VIA ERITREA 62, I-20157 MILAN, ITALY |
Addresses:
1. UNIV LA SAPIENZA, DEPT BIOPATHOL, I-00100 ROME, ITALY |
| Publisher: ELSEVIER SCI LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, OXON, ENGLAND OX5 1GB |
| Subject Category: Immunology |
| IDS Number: JB978 |
| ISSN: 0167-5699 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |