| | |  | | | | Record from Web of Science® | | | | | | |
| THE EMERGENCE OF THE CHAPERONE MACHINES |
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| Author(s): GEORGOPOULOS C |
| Source: TRENDS IN BIOCHEMICAL SCIENCES Volume: 17 Issue: 8 Pages: 295-299 Published: AUG 1992 |
| Times Cited: 221 References: 32 |
| Abstract: To ensure proper polypeptide folding, oligomerization and transport, elaborate molecular 'chaperone machines' have evolved. These machines are usually composed of a major chaperone protein that binds promiscuously to nascent, unfolded, misfolded or aggregated polypeptides and a set of chaperone 'cohorts', whose function is to enhance efficiency and ensure recycling. These chaperone machines can function by themselves or synergistically to carry out their various tasks. |
| Document Type: Article |
| Language: English |
| Reprint Address: GEORGOPOULOS, C (reprint author), UNIV GENEVA, HLTH SCI CTR, DEPT BIOCHIM MED, 1 RUE MICHEL SERVET, CH-1211 GENEVA 4, SWITZERLAND |
| Publisher: ELSEVIER SCI LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, OXON, ENGLAND OX5 1GB |
| Subject Category: Biochemistry & Molecular Biology |
| IDS Number: JH637 |
| ISSN: 0968-0004 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |