| | |  | | | | Record from Web of Science® | | | | | | |
| WORLDWIDE PREVALENCE OF LENTIVIRUS INFECTION IN WILD FELINE SPECIES - EPIDEMIOLOGIC AND PHYLOGENETIC ASPECTS |
|
|
| Author(s): OLMSTED RA, LANGLEY R, ROELKE ME, GOEKEN RM, ADGERJOHNSON D, GOFF JP, ALBERT JP, PACKER C, LAURENSON MK, CARO TM, SCHEEPERS L, WILDT DE, BUSH M, MARTENSON JS, OBRIEN SJ |
| Source: JOURNAL OF VIROLOGY Volume: 66 Issue: 10 Pages: 6008-6018 Published: OCT 1992 |
| Times Cited: 113 References: 47 |
| Abstract: The natural occurrence of lentiviruses closely related to feline immunodeficiency virus (FIV in nondomestic felid species is shown here to be worldwide. Cross-reactive antibodies to FIV were common in several free-ranging populations of large cats, including East African lions and cheetahs of the Serengeti ecosystem and in puma (also called cougar or mountain lion) populations throughout North America. Infectious puma lentivirus (PLV) was isolated from several Florida panthers, a severely endangered relict puma subspecies inhabiting the Big Cypress Swamp and Everglades ecosystems in southern Florida. Phylogenetic analysis of PLV genomic sequences from disparate geographic isolates revealed appreciable divergence from domestic cat FIV sequences as well as between PLV sequences found in different North American locales. The level of sequence divergence between PLV and FIV was greater than the level of divergence between human and certain simian immunodeficiency viruses, suggesting that the transmission of FIV between feline species is infrequent and parallels in time the emergence of HIV from simian ancestors. |
| Document Type: Article |
| Language: English |
Addresses:
1. NCI, FREDERICK CANC RES & DEV CTR, VIRAL CARCINOGENESIS LAB, FREDERICK, MD 21702 USA
2. GEORGETOWN UNIV, DEPT MICROBIOL, DIV MOLEC VIROL & IMMUNOL, WASHINGTON, DC 20057 USA
3. NIAID, INFECT DIS LAB, ROCKVILLE, MD 20852 USA
4. FLORIDA GAME & FRESHWATER FISH COMMISS, WILDLIFE RES LAB, GAINESVILLE, FL 32601 USA
5. UNIV MINNESOTA, DEPT ECOL & BEHAV BIOL, MINNEAPOLIS, MN 55455 USA
6. UNIV CAMBRIDGE, DEPT ZOOL, CAMBRIDGE CB2 3EJ, ENGLAND
7. UNIV CALIF DAVIS, DEPT WILDLIFE & FISHERIES BIOL, DAVIS, CA 95616 USA
8. ETOSHA ECOL INST, OUTJO, NAMIBIA
9. SMITHSONIAN INST, NATL ZOOL PK, DEPT ANIM HLTH, WASHINGTON, DC 20008 USA |
| Publisher: AMER SOC MICROBIOLOGY, 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 |
| Subject Category: Virology |
| IDS Number: JN267 |
| ISSN: 0022-538X |
|
| | | | | | | | | Record from Web of Science® | | | | | | | | | |