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| CONTINUUM OF OVERLAPPING CLONES SPANNING THE ENTIRE HUMAN CHROMOSOME-21Q |
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| Author(s): CHUMAKOV I, RIGAULT P, GUILLOU S, OUGEN P, BILLAUT A, GUASCONI G, GERVY P, LEGALL I, SOULARUE P, GRINAS L, BOUGUELERET L, BELLANNECHANTELOT C, LACROIX B, BARILLOT E, GESNOUIN P, POOK S, VAYSSEIX G, FRELAT G, SCHMITZ A, SAMBUCY JL, BOSCH A, ESTIVILL X, WEISSENBACH J, VIGNAL A, RIETHMAN H, COX D, PATTERSON D, GARDINER K, HATTORI M, SAKAKI Y, ICHIKAWA H, OHKI M, LEPASLIER D, HEILIG R, ANTONARAKIS S, COHEN D |
| Source: NATURE Volume: 359 Issue: 6394 Pages: 380-387 Published: OCT 1 1992 |
| Times Cited: 459 References: 28 |
| Abstract: A continuous array of overlapping clones covering the entire human chromosome 21q was constructed from human yeast artificial chromosome libraries using sequence-tagged sites as landmarks specifically detected by polymerase chain reaction. The yeast artificial chromosome contiguous unit starts with pericentromeric and ends with subtelomeric loci of 21q. The resulting order of sequence-tagged sites is consistent with other physical and genetic mapping data. This set of overlapping clones will promote our knowledge of the structure of this chromosome and the function of its genes. |
| Document Type: Article |
| Language: English |
Addresses:
1. CTR ETUD POLYMORPHISME HUMAIN, 27 RUE JULIETTE DODU, F-75010 PARIS, FRANCE
2. GENETHON, F-91002 EVRY, FRANCE
3. CEA, F-92260 FONTENAY ROSES, FRANCE
4. HOSP DURAN & REYNALS, INST RECERCA ONCOL, E-08907 BARCELONA, SPAIN
5. INST PASTEUR, CNRS, URA 1445, F-75724 PARIS, FRANCE
6. UNIV CALIF SAN FRANCISCO, NEUROGENET LAB, SAN FRANCISCO, CA 94143 USA
7. ELEANOR ROOSEVELT INST, DENVER, CO 80206 USA
8. WISTAR INST, PHILADELPHIA, PA 19104 USA
9. UNIV TOKYO, INST MED SCI, TOKYO 108, JAPAN
10. LAB GENET MOLEC EUCARYOTES, INSERM, U184, STRASBOURG, FRANCE
11. JOHNS HOPKINS UNIV, SCH MED, CTR MED GENET, BALTIMORE, MD 21205 USA
12. SAITAMA CANC CTR, RES INST, INA, SAITAMA 362 JAPAN |
| Publisher: MACMILLAN MAGAZINES LTD, PORTERS SOUTH, 4 CRINAN ST, LONDON, ENGLAND N1 9XW |
| Subject Category: Multidisciplinary Sciences |
| IDS Number: JQ624 |
| ISSN: 0028-0836 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |