| | |  | | | | Record from Web of Science® | | | | | | |
| CREATIVE BLOCKS - CELL-CYCLE CHECKPOINTS AND FEEDBACK CONTROLS |
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| Author(s): MURRAY AW |
| Source: NATURE Volume: 359 Issue: 6396 Pages: 599-604 Published: OCT 15 1992 |
| Times Cited: 608 References: 84 |
| Abstract: Before division, cells must ensure that they finish DNA replication, DNA repair and chromosome segregation. They do so by using feedback controls which can detect the failure to complete replication, repair or spindle assembly to arrest the progress of the cell cycle at one of three checkpoints. Failures in feedback controls can contribute to the generation of cancer. |
| Document Type: Review |
| Language: English |
| Reprint Address: MURRAY, AW (reprint author), UNIV CALIF SAN FRANCISCO, DEPT PHYSIOL, BOX 0444, SAN FRANCISCO, CA 94143 USA |
| Publisher: MACMILLAN MAGAZINES LTD, PORTERS SOUTH, 4 CRINAN ST, LONDON, ENGLAND N1 9XW |
| Subject Category: Multidisciplinary Sciences |
| IDS Number: JT824 |
| ISSN: 0028-0836 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |