| | |  | | | | Record from Web of Science® | | | | | | |
| INTERLEUKIN-6 AND ITS RECEPTOR - A PARADIGM FOR CYTOKINES |
|
|
| Author(s): KISHIMOTO T, AKIRA S, TAGA T |
| Source: SCIENCE Volume: 258 Issue: 5082 Pages: 593-597 Published: OCT 23 1992 |
| Times Cited: 668 References: 127 |
| Abstract: Many cytokines and cytokine receptors involved in the regulation of hematopoiesis, immune responses, and inflammation have been identified and characterized at the molecular level. Several characteristic features of cytokines, such as pleiotropy and redundancy, are now more clearly understood on the basis of their molecular structures. Accumulating evidence has demonstrated an intimate link between cytokines and various diseases such as allergy, autoimmune diseases, and cancer. The pathogenesis of these diseases and therapies to treat them will be discussed based on insights derived from cytokine research. |
| Document Type: Article |
| Language: English |
| Reprint Address: KISHIMOTO, T (reprint author), OSAKA UNIV, SCH MED, DEPT INTERNAL MED 3, OSAKA 553, JAPAN |
Addresses:
1. OSAKA UNIV, INST MOLEC & CELLULAR BIOL, SUITA, OSAKA 565 JAPAN |
| Publisher: AMER ASSOC ADVANCEMENT SCIENCE, 1200 NEW YORK AVE, NW, WASHINGTON, DC 20005 |
| Subject Category: Multidisciplinary Sciences |
| IDS Number: JU745 |
| ISSN: 0036-8075 |
|
| | | | | | | | | Record from Web of Science® | | | | | | | | | |