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ENDOCYTOSIS OF CALCIUM-OXALATE CRYSTALS AND PROLIFERATION OF RENAL TUBULAR EPITHELIAL-CELLS IN A PATIENT WITH TYPE-1 PRIMARY HYPEROXALURIA
Author(s): LIESKE JC, SPARGO BH, TOBACK FG
Source: JOURNAL OF UROLOGY    Volume: 148    Issue: 5    Pages: 1517-1519    Published: NOV 1992  
Times Cited: 58     References: 16     
Abstract: A patient with primary hyperoxaluria who received a liver-kidney transplant is presented. A postoperative renal biopsy showed apparent tubular cell endocytosis of calcium oxalate crystals and cell proliferation, indicating that renal epithelial cells do not perceive urinary crystals as inert. Such cellular responses to crystals may have a role in nephrolithiasis.
Document Type: Article
Language: English
Addresses:
1. UNIV CHICAGO, DEPT MED, 5841 S MARYLAND AVE, MC 5100, CHICAGO, IL 60637 USA
2. UNIV CHICAGO, DEPT PATHOL, CHICAGO, IL 60637 USA
Publisher: WILLIAMS & WILKINS, 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436
Subject Category: Urology & Nephrology
IDS Number: JW460
ISSN: 0022-5347
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