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THE GENE-PROTEIN DATABASE OF ESCHERICHIA-COLI - EDITION 5
Author(s): VANBOGELEN RA, SANKAR P, CLARK RL, BOGAN JA, NEIDHARDT FC
Source: ELECTROPHORESIS    Volume: 13    Issue: 12    Pages: 1014-1054    Published: DEC 1992  
Times Cited: 105     References: 42     
Abstract: The gene-protein database of Escherichia coli is both an index relating a gene to its protein product on two-dimensional gels, and a catalog of information about the function, regulation, and genetics of individual proteins obtained from two-dimensional gel analysis or collated from the literature. Edition 5 has 102 new entries-a 15% increase in the number of annotated two-dimensional gel spots. The large increase in this edition was accomplished in part by the use of a new method for expression analysis of ordered segments of the E. coli genome, which has resulted in linking 50 gel spots to their genes (or open reading frames) and another 45 to specific regions of the chromosome awaiting the availability of DNA sequence information. Communication of information from the scientific community resulted in additional identifications and regulatory information. To increase accessibility of the database it has been placed in the repository at the National Center for Biotechnology Information (NCBI) at the National Library of Medicine under the name ECO2DBASE. It will be updated twice yearly. This edition of the gene-protein database is estimated to contain entries for one-sixth of the protein-encoding genes of E. coli.
Document Type: Article
Language: English
Addresses:
1. UNIV MICHIGAN, SCH MED, DEPT MICROBIOL & IMMUNOL, ANN ARBOR, MI 48109 USA
Publisher: VCH PUBLISHERS INC, 303 NW 12TH AVE, DEERFIELD BEACH, FL 33442-1788
Subject Category: Biochemical Research Methods; Chemistry, Analytical
IDS Number: KL355
ISSN: 0173-0835
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