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AIDS-MYELOPATHY - A NEUROPATHOLOGICAL STUDY
Author(s): BERGMANN M, GULLOTTA F, KUCHELMEISTER K, MASINI T, ANGELI G
Source: PATHOLOGY RESEARCH AND PRACTICE    Volume: 189    Issue: 1    Pages: 58-65    Published: FEB 1993  
Times Cited: 7     References: 45     
Abstract: Vacuolar myelopathy belongs to the AIDS-associated diseases. It is characterized by vacuolation and infiltration of the long tracts of the spinal cord by macrophages. The clinical and morphological findings of 8 AIDS-patients with vacuolar myelopathy are reported here. The syndrome developed during the final stages of AIDS and was associated with HIV-encephalopathy in S cases. The vacuoles were mainly due to intramyelinic swelling and vacuolation. Vacuolated macrophages and axons contributed only to a minor degree. In one case only, HIV-antigens were detected immunohistochemically. The results are discussed in the light of modern pathogenetical concepts of HIV-related diseases.
Document Type: Article
Language: English
Reprint Address: BERGMANN, M (reprint author), UNIV MUNSTER, DEPT NEUROPATHOL, DOMAGKSTR 17, W-4400 MUNSTER, GERMANY
Addresses:
1. DEPT PATHOL, NOVARA, ITALY
2. UNIV MILAN, DEPT PATHOL, I-20122 MILAN, ITALY
Publisher: GUSTAV FISCHER VERLAG, VILLENGANG 2, D-07745 JENA, GERMANY
Subject Category: Pathology
IDS Number: KT701
ISSN: 0344-0338
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