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GRANULATION-TISSUE POLYPOSIS ASSOCIATED WITH CARCINOID-TUMORS OF THE SMALL-INTESTINE
Author(s): ALLIBONE RO, HOFFMAN J, GOSNEY JR, HELLIWELL TR
Source: HISTOPATHOLOGY    Volume: 22    Issue: 5    Pages: 475-480    Published: MAY 1993  
Times Cited: 3     References: 19     
Abstract: We report two patients with ileal carcinoid tumours which were associated with polyps due to mucosal granulation tissue proliferation. In both cases the tumours had extensively infiltrated the small bowel wall and mesentery, and one had hepatic metastases. The mucosal surface of each specimen showed numerous, pale brown, sessile polyps which were restricted to the intestinal segment involved by carcinoid tumour, although not always closely related to neoplastic cells. The polyps were formed by the proliferation of capillaries, smooth muscle cells and myofibroblasts as demonstrated by immunohistochemistry and electronmicroscopy.
Document Type: Article
Language: English
Addresses:
1. UNIV EXETER, ROYAL DEVON & EXETER HOSP, DEPT HISTOPATHOL, EXETER EX4 4RJ, DEVON ENGLAND
2. UNIV EXETER, POSTGRAD MED SCH, EXETER EX4 4RJ, DEVON ENGLAND
3. UNIV LIVERPOOL, DEPT PATHOL, LIVERPOOL L69 3BX, ENGLAND
Publisher: BLACKWELL SCIENCE LTD, OSNEY MEAD, OXFORD, OXON, ENGLAND OX2 0EL
Subject Category: Cell Biology; Pathology
IDS Number: LF489
ISSN: 0309-0167
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