| | |  | | | | Record from Web of Science® | | | | | | |
| 3-DIMENSIONAL STRUCTURE OF MYOSIN SUBFRAGMENT-1 - A MOLECULAR MOTOR |
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| Author(s): RAYMENT I, RYPNIEWSKI WR, SCHMIDTBASE K, SMITH R, TOMCHICK DR, BENNING MM, WINKELMANN DA, WESENBERG G, HOLDEN HM |
| Source: SCIENCE Volume: 261 Issue: 5117 Pages: 50-58 Published: JUL 2 1993 |
| Times Cited: 1,476 References: 74 |
| Abstract: Directed movement is a characteristic of many living organisms and occurs as a result of the transformation of chemical energy into mechanical energy. Myosin is one of three families of molecular motors that are responsible for cellular motility. The three-dimensional structure of the head portion of myosin, or subfragment-1, which contains both the actin and nucleotide binding sites, is described. This structure of a molecular motor was determined by single crystal x-ray diffraction. The data provide a structural framework for understanding the molecular basis of motility. |
| Document Type: Article |
| Language: English |
| Reprint Address: RAYMENT, I (reprint author), UNIV WISCONSIN, DEPT BIOCHEM, 1710 UNIV AVE, MADISON, WI 53705 USA |
Addresses:
1. UNIV WISCONSIN, INST ENZYME RES, MADISON, WI 53705 USA
2. ROBERT WOOD JOHNSON MED SCH, DEPT PATHOL, PISCATAWAY, NJ 08854 USA |
| Publisher: AMER ASSOC ADVANCEMENT SCIENCE, 1200 NEW YORK AVE, NW, WASHINGTON, DC 20005 |
| Subject Category: Multidisciplinary Sciences |
| IDS Number: LK434 |
| ISSN: 0036-8075 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |