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| DETERMINING A MINIMAL IMPORTANT CHANGE IN A DISEASE-SPECIFIC QUALITY-OF-LIFE QUESTIONNAIRE |
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| Author(s): JUNIPER EF, GUYATT GH, WILLAN A, GRIFFITH LE |
| Source: JOURNAL OF CLINICAL EPIDEMIOLOGY Volume: 47 Issue: 1 Pages: 81-87 Published: JAN 1994 |
| Times Cited: 713 References: 12 |
| Abstract: This study was carried out to determine whether the minimal important difference, in evaluative quality of life instruments which use a 7-point scale, is similar across individual domains and for both improvement and deterioration. Thirty nine adults with asthma were studied, using an 8 week cohort with assessments at 0, 4 and g weeks. The outcomes were the Asthma Quality of Life Questionnaire and global rating of change. For overall asthma-specific quality of life and for all individual domains (activities, emotions, symptoms), the minimal important difference of quality of life score per item was very close to 0.5 (range: 0.42-0.58); differences of approximately 1.0 represented a moderate change (range: 0.77-1.51); differences greater than 1.5 represented large changes. Changes for improvement and deterioration were very similar. The changes in quality of life score that represent a minimal important difference are very similar to those observed for other evaluative instruments. The observation that the minimal important difference is consistent across domains and for both improvement and deterioration will facilitate interpretation of results of studies examining quality of life. |
| Document Type: Article |
| Language: English |
| Reprint Address: JUNIPER, EF (reprint author), MCMASTER UNIV, MED CTR, DEPT CLIN EPIDEMIOL & BIOSTAT, 1200 MAIN ST W, HAMILTON L8N 3Z5, ON CANADA |
Addresses:
1. MCMASTER UNIV, MED CTR, DEPT MED, HAMILTON L8N 3Z5, ON CANADA |
| Publisher: PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB |
| Subject Category: Public, Environmental & Occupational Health |
| IDS Number: MT278 |
| ISSN: 0895-4356 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |