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| THE GENE FOR THE RETINAL-PIGMENT EPITHELIUM-SPECIFIC PROTEIN RPE65 IS LOCALIZED TO HUMAN 1P31 AND MOUSE-3 |
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| Author(s): HAMEL CP, JENKINS NA, GILBERT DJ, COPELAND NG, REDMOND TM |
| Source: GENOMICS Volume: 20 Issue: 3 Pages: 509-512 Published: APR 1994 |
| Times Cited: 45 References: 10 |
| Abstract: The human and murine chromosomal localization for the gene for the retinal pigment epithelium-specific protein RPE65 was determined. Using interspecific backcross analysis, we mapped Rpe65 to the distal end of mouse chromosome 3. In the human, using a human-hamster hybrid panel, RPE65 was mapped to chromosome 1. By the use of fluorescence in situ hybridization, this localization was refined to 1p31. The mouse and human loci for this potential candidate gene for hereditary retinal disease do not match those of any known disease in mouse or man. (C) 1994 Academic Press, Inc. |
| Document Type: Note |
| Language: English |
Addresses:
1. NEI, LRCMB, BETHESDA, MD 20892 USA
2. NCI, FREDERICK CANC RES & DEV CTR, ABL BASIC RES PROGRAM, MAMMALIAN GENET LAB, FREDERICK, MD 21702 USA |
| Publisher: ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS, 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 |
| Subject Category: Biotechnology & Applied Microbiology; Genetics & Heredity |
| IDS Number: NF578 |
| ISSN: 0888-7543 |
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