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PROBING THE STRUCTURE OF FOLDING INTERMEDIATES
Author(s): EVANS PA, RADFORD SE
Source: CURRENT OPINION IN STRUCTURAL BIOLOGY    Volume: 4    Issue: 1    Pages: 100-106    Published: FEB 1994  
Times Cited: 88     References: 53     
Abstract: The description of protein folding mechanisms in terms of the structures of well defined, partially folded intermediates is a major objective in structural biology. Despite the fleeting existence of intermediates and the fact that their structures are unlikely to be uniquely defined, significant advances in our understanding of protein folding pathways have been made in the last year based on a variety of physical methods.
Document Type: Article
Language: English
Reprint Address: EVANS, PA (reprint author), UNIV CAMBRIDGE, DEPT BIOCHEM, TENNIS COURT RD, CAMBRIDGE CB2 1QW, ENGLAND
Addresses:
1. UNIV OXFORD, NEW CHEM LAB, OXFORD OX1 3QT, ENGLAND
Publisher: CURRENT BIOLOGY LTD, 34-42 CLEVELAND STREET, LONDON, ENGLAND W1P 6LB
Subject Category: Biochemistry & Molecular Biology; Cell Biology
IDS Number: NF779
ISSN: 0959-440X
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