| | |  | | | | Record from Web of Science® | | | | | | |
| CHEMOTHERAPY PROLONGS SURVIVAL IN INOPERABLE PANCREATIC-CARCINOMA |
|
|
| Author(s): PALMER KR, KERR M, KNOWLES G, CULL A, CARTER DC, LEONARD RCF |
| Source: BRITISH JOURNAL OF SURGERY Volume: 81 Issue: 6 Pages: 882-885 Published: JUN 1994 |
| Times Cited: 176 References: 22 |
| Abstract: Forty-three patients with irrescetable advanced pancreatic cancer were randomized to receive chemotherapy using a combination of 5-fluorouracil, Adriamycin and mitomycin or no chemotherapy. Groups were well matched with regard to age, extent of disease and performance status on entry. Chemotherapy was well tolerated and, although common, side-effects were usually mild. Psychological measurements based on the Hospital Anxiety and Depression score were made in 31 patients. These showed significantly less depression but not anxiety in the treated group immediately after randomization and following 2 months of chemotherapy. Median survival in the treated group was 33 (range 9-80) weeks compared with 15 (range 1-62) weeks in the untreated group (P < 0.002). Chemotherapy should be considered in all patients presenting with advanced inoperable pancreatic cancer. |
| Document Type: Article |
| Language: English |
| Reprint Address: PALMER, KR (reprint author), WESTERN GEN HOSP, GASTROINTESTINAL UNIT, GASTRINTESTINAL ANNEXE, CREWE RD, EDINBURGH EH4 2XU, MIDLOTHIAN SCOTLAND |
Addresses:
1. WESTERN GEN HOSP, DEPT CLIN ONCOL, EDINBURGH EH4 2XU, MIDLOTHIAN SCOTLAND
2. WESTERN GEN HOSP, DEPT PSYCHOL, EDINBURGH EH4 2XU, MIDLOTHIAN SCOTLAND
3. UNIV EDINBURGH, ROYAL INFIRM, DEPT SURG, EDINBURGH, SCOTLAND |
| Publisher: BLACKWELL SCIENCE LTD, OSNEY MEAD, OXFORD, OXON, ENGLAND OX2 0EL |
| Subject Category: Surgery |
| IDS Number: NR792 |
| ISSN: 0007-1323 |
|
| | | | | | | | | Record from Web of Science® | | | | | | | | | |