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| HEPATITIS-C TRANSMISSION IN A HEMODIALYSIS UNIT - MOLECULAR EVIDENCE FOR SPREAD OF VIRUS AMONG PATIENTS NOT SHARING EQUIPMENT |
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| Author(s): ALLANDER T, MEDIN C, JACOBSON SH, GRILLNER L, PERSSON MAA |
| Source: JOURNAL OF MEDICAL VIROLOGY Volume: 43 Issue: 4 Pages: 415-419 Published: AUG 1994 |
| Times Cited: 155 References: 22 |
| Abstract: Three cases of simultaneous seroconversion to hepatitis C virus (HCV) in a hemodialysis unit initiated the investigation of the viral strains of 14 seropositive patients in the unit by nucleotide sequencing. The results showed that five patients had been infected with the same viral strain, and indicated that two other patients were sharing a second strain. Transmission was not related to blood transfusions and not associated with the dialysis machines, but occurred between patients treated on the same shift. The number of cases was higher than expected from the serological data. Thus, spread of virus may occur at high frequencies in environments where parenteral routes are made accessible, in spite of rigorous preventive measures. This may raise concern that non-transfusion associated spread of HCV may be present and unnoticed in several hospital settings. (C) 1994 Wiley-Liss, Inc. |
| Document Type: Article |
| Language: English |
Addresses:
1. KAROLINSKA INST, KAROLINSKA HOSP, ROLF LUFT CTR DIABET RES, DEPT MED, S-17176 STOCKHOLM, SWEDEN
2. KAROLINSKA INST, KAROLINSKA HOSP, DEPT CLIN MICROBIOL, S-10401 STOCKHOLM, SWEDEN |
| Publisher: WILEY-LISS, DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 |
| Subject Category: Virology |
| IDS Number: NZ403 |
| ISSN: 0146-6615 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |