| | |  | | | | Record from Web of Science® | | | | | | |
| THE T-GENES IN EMBRYOGENESIS |
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| Author(s): HERRMANN BG, KISPERT A |
| Source: TRENDS IN GENETICS Volume: 10 Issue: 8 Pages: 280-286 Published: AUG 1994 |
| Times Cited: 137 References: 33 |
| Abstract: Since its identification in 1927, the mouse T (Brachyury) locus has been implicated in mesoderm formation and and notochord differentiation Recent work; has demonstrated that this gene encodes a putative transcription factor expressed specifically in nascent mesoderm and in the differentiating notochord. Homologous genes have been cloned from the frog Xenopus laevis, the zebrafish Brachydanio rerio and the ascidian Halocynthia roretzi. The T gene is an important tool for elucidating mesodermal and embryonic pattern formation. |
| Document Type: Review |
| Language: English |
| Reprint Address: HERRMANN, BG (reprint author), MAX PLANCK INST ENTWICKLUNGSBIOL, BIOCHEM ABT, SPEMANSTR 35-II, D-72076 TUBINGEN, GERMANY |
| Publisher: ELSEVIER SCI LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, OXON, ENGLAND OX5 1GB |
| Subject Category: Genetics & Heredity |
| IDS Number: NZ537 |
| ISSN: 0168-9525 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |