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| THE EVOLUTIONARY DYNAMICS OF REPETITIVE DNA IN EUKARYOTES |
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| Author(s): CHARLESWORTH B, SNIEGOWSKI P, STEPHAN W |
| Source: NATURE Volume: 371 Issue: 6494 Pages: 215-220 Published: SEP 15 1994 |
| Times Cited: 719 References: 102 |
| Abstract: Repetitive DNA sequences form a large portion of the genomes of eukaryotes. The 'selfish DNA' hypothesis proposes that they are maintained by their ability to replicate within the genome. The behaviour of repetitive sequences can result in mutations that cause genetic diseases, and confer significant fitness losses on the organism. Features of the organization of repetitive sequences in eukaryotic genomes, and their distribution in natural populations, reflect the evolutionary forces acting on selfish DNA. |
| Document Type: Review |
| Language: English |
| Reprint Address: CHARLESWORTH, B (reprint author), UNIV CHICAGO, DEPT ECOL & EVOLUT, 1101 E 57TH ST, CHICAGO, IL 60637 USA |
Addresses:
1. MICHIGAN STATE UNIV, CTR MICROBIAL ECOL, E LANSING, MI 48824 USA
2. UNIV MARYLAND, DEPT ZOOL, COLLEGE PK, MD 20742 USA |
| Publisher: MACMILLAN MAGAZINES LTD, PORTERS SOUTH, 4 CRINAN ST, LONDON, ENGLAND N1 9XW |
| Subject Category: Multidisciplinary Sciences |
| IDS Number: PG290 |
| ISSN: 0028-0836 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |