| | |  | | | | Record from Web of Science® | | | | | | |
| CORRELATION BETWEEN CONTRAST ENHANCEMENT IN DYNAMIC MAGNETIC-RESONANCE-IMAGING OF THE BREAST AND TUMOR ANGIOGENESIS |
|
|
| Author(s): FROUGE C, GUINEBRETIERE JM, CONTESSO G, DIPAOLA R, BLERY M |
| Source: INVESTIGATIVE RADIOLOGY Volume: 29 Issue: 12 Pages: 1043-1049 Published: DEC 1994 |
| Times Cited: 95 References: 18 |
| Abstract: RATIONALE AND OBJECTIVE. The authors determined the relation between tumor angiogenesis in small invasive breast carcinoma and contrast enhancement on magnetic resonance imaging (MRI) after gadolinium injection. MATERIALS AND METHODS. Magnetic resonance imaging was performed before surgery in a prospective study of 20 patients who had a small palpable lump, Spin-echo sequences after injection of gadolinium were studied by factor analysis of medical image sequences and were compared with a histologic quantification of tumor angiogenesis after immunocytochemical staining.
RESULTS. In nine cases, there was good correlation between the MRI and the histologic plane. In four patients, an early factor was found on MRI, This factor was related to a high concentration of arterioles located in the stroma or, in one patient, to the intratumor repair process.
CONCLUSION. Early enhancement correlated well with the number of vessels determined histologically.
|
| Document Type: Article |
| Language: English |
| Reprint Address: FROUGE, C (reprint author), HOP BICETRE, DEPT RADIOL, SERV RADIOL CENT, 78 RUE GEN LECLERC, F-94275 LE KREMLIN BICETRE, FRANCE |
Addresses:
1. INSERM, VILLEJUIF, FRANCE
2. INST GUSTAVE ROUSSY, DEPT PATHOL, VILLEJUIF, FRANCE |
| Publisher: LIPPINCOTT-RAVEN PUBL, 227 EAST WASHINGTON SQUARE, PHILADELPHIA, PA 19106 |
| Subject Category: Radiology, Nuclear Medicine & Medical Imaging |
| IDS Number: QG420 |
| ISSN: 0020-9996 |
|
| | | | | | | | | Record from Web of Science® | | | | | | | | | |