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ESOPHAGEAL CANCER AND AMPLIFICATION OF THE HUMAN CYCLIN-D GENE CCND1/PRAD1
Author(s): ADELAIDE J, MONGES G, DERDERIAN C, SEITZ JF, BIRNBAUM D
Source: BRITISH JOURNAL OF CANCER    Volume: 71    Issue: 1    Pages: 64-68    Published: JAN 1995  
Times Cited: 68     References: 49     
Abstract: The human CCND1/PRAD1 gene, located in the 11q13 chromosomal region, encodes a cyclin D protein with potential oncogenic capacity and is involved in several human malignancies. The amplification and expression status of CCND1 was investigated in a series of oesophageal tumours. CCND1 is amplified in 54% and overexpressed in 63% of the tumours of the squamous cell type.
Document Type: Article
Language: English
Addresses:
1. INSERM, U119, F-13009 MARSEILLE, FRANCE
2. INST J PAOLI I CALMETTES, BIOL TUMEURS LAB, F-13009 MARSEILLE, FRANCE
3. INST J PAOLI I CALMETTES, DEPT ANAT PATHOL, MARSEILLE, FRANCE
4. INST J PAOLI I CALMETTES, DEPT ONCOL DIGEST, MARSEILLE, FRANCE
Publisher: STOCKTON PRESS, HOUNDMILLS, BASINGSTOKE, HANTS, ENGLAND RG21 2XS
Subject Category: Oncology
IDS Number: QA578
ISSN: 0007-0920
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