| INTERMEDIATE FILAMENTS IN DISEASE |
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| Author(s): MCLEAN WHI, LANE EB |
| Source: CURRENT OPINION IN CELL BIOLOGY Volume: 7 Issue: 1 Pages: 118-125 Published: FEB 1995 |
| Times Cited: 208 References: 48 |
| Abstract: Intermediate filaments are major structural proteins encoded by a large multigene family. Their tissue-specific expression makes them important in studies of development, differentiation and pathology. Most intermediate filaments are keratins; recent discoveries of keratin mutations in a range of genetic skin disorders have clarified their role as providing essential structural support for cells in different physical settings. |
| Document Type: Article |
| Language: English |
| Reprint Address: MCLEAN, WHI (reprint author), UNIV DUNDEE, INST MED SCI, DEPT ANAT & PHYSIOL, CANC RES CAMPAIGN CELL STRUCT RES GRP, DUNDEE DD1 4HN, SCOTLAND |
| Publisher: CURRENT BIOLOGY LTD, 34-42 CLEVELAND STREET, LONDON, ENGLAND W1P 6LB |
| Subject Category: Cell Biology |
| IDS Number: QE873 |
| ISSN: 0955-0674 |