| | |  | | | | Record from Web of Science® | | | | | | |
| PROTEIN MODULES AND SIGNALING NETWORKS |
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| Author(s): PAWSON T |
| Source: NATURE Volume: 373 Issue: 6515 Pages: 573-580 Published: FEB 16 1995 |
| Times Cited: 1,903 References: 131 |
| Abstract: Communication between cells assumes particular importance in multicellular organisms. The growth, migration and differentiation of cells in the embryo, and their organization into specific tissues, depend on signals transmitted from one cell to another. In the adult, cell signalling orchestrates normal cellular behaviour and responses to wounding and infection. The consequences of breakdowns in this signalling underlie cancer, diabetes and disorders of the immune and cardiovascular systems. Conserved protein domains that act as key regulatory participants in many of these different signalling pathways are highlighted. |
| Document Type: Review |
| Language: English |
| Reprint Address: PAWSON, T (reprint author), MT SINAI HOSP, SAMUEL LUNENFELD RES INST, DIV MOLEC & DEV BIOL, 600 UNIV AVE, TORONTO, ON M5G 1X5 CANADA |
| Publisher: MACMILLAN MAGAZINES LTD, 4 LITTLE ESSEX STREET, LONDON, ENGLAND WC2R 3LF |
| Subject Category: Multidisciplinary Sciences |
| IDS Number: QG997 |
| ISSN: 0028-0836 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |