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OBSERVER VARIABILITY IN THE HISTOLOGIC ASSESSMENT OF ORAL PREMALIGNANT LESIONS
Author(s): KARABULUT A, REIBEL J, THERKILDSEN MH, PRAETORIUS F, NIELSEN HW, DABELSTEEN E
Source: JOURNAL OF ORAL PATHOLOGY & MEDICINE    Volume: 24    Issue: 5    Pages: 198-200    Published: MAY 1995  
Times Cited: 86     References: 27     
Abstract: Histopathologic examination of oral leukoplakias has a major impact on the assessment of prognosis and treatment planning. We investigated the extent of agreement in grading epithelial dysplasia between pathologists with the same or different educational backgrounds. Two general pathologists and two oral pathologists were each given 100 sections of oral leukoplakia to grade from no dysplasia to carcinoma in-situ. The interobserver agreement rates were in the range of 49% to 69%. The calculated kappa values were in the range of 27% to 45%, showing poor to moderate agreement between the pathologists, When comparing the kappa values between the two pairs of pathologists with the same education, these values did not diverge from the general level of kappa values, indicating that the interobserver variability was due to individual differences rather than to educational background.
Document Type: Article
Language: English
Reprint Address: KARABULUT, A (reprint author), UNIV COPENHAGEN, SCH DENT, DEPT ORAL PATHOL & MED, NORRE ALLE 20, DK-2200 COPENHAGEN N, DENMARK
Addresses:
1. UNIV COPENHAGEN, DEPT ORAL DIAGNOST, DK-2200 COPENHAGEN N, DENMARK
2. UNIV COPENHAGEN HOSP, DEPT ORAL MED & ORAL SURG, DK-2100 COPENHAGEN, DENMARK
3. UNIV COPENHAGEN HOSP, DEPT PATHOL, DK-2100 COPENHAGEN, DENMARK
Publisher: MUNKSGAARD INT PUBL LTD, 35 NORRE SOGADE, PO BOX 2148, DK-1016 COPENHAGEN, DENMARK
Subject Category: Dentistry, Oral Surgery & Medicine; Pathology
IDS Number: QX631
ISSN: 0904-2512
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