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| AN AUTOSOMAL GENETIC-LINKAGE MAP OF THE SHEEP GENOME |
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| Author(s): CRAWFORD AM, DODDS KG, EDE AJ, PIERSON CA, MONTGOMERY GW, GARMONSWAY HG, BEATTIE AE, DAVIES K, MADDOX JF, KAPPES SW, STONE RT, NGUYEN TC, PENTY JM, LORD EA, BROOM JE, BUITKAMP J, SCHWAIGER W, EPPLEN JT, MATTHEW P, MATTHEWS ME, HULME DJ, BEH KJ, MCGRAW RA, BEATTIE CW |
| Source: GENETICS Volume: 140 Issue: 2 Pages: 703-724 Published: JUN 1995 |
| Times Cited: 252 References: 101 |
| Abstract: We report the first extensive ovine genetic linkage map covering 2070 cM of the sheep genome. The map was generated from the linkage analysis of 246 polymorphic markers, in nine three-generation full-sib pedigrees, which make up the AgResearch International Mapping Flock. We have exploited many markers from cattle so that valuable comparisons between these two ruminant linkage maps can be made. The markers, used in the segregation analyses, comprised 86 anonymous microsatellite markers derived from the sheep genome, 126 anonymous microsatellites from cattle, one from deer, and 33 polymorphic markers of various types associated with known genes. The maximum number of informative meioses within the mapping flock was 222. The average number of informative meioses per marker was 140 (range 18-209). Linkage groups have been assigned to all 26 sheep autosomes. |
| Document Type: Review |
| Language: English |
| Reprint Address: CRAWFORD, AM (reprint author), UNIV OTAGO, DEPT BIOCHEM, AGRES MOLEC BIOL UNIT, DUNEDIN, NEW ZEALAND |
Addresses:
1. UNIV OTAGO, CTR GENE RES, DUNEDIN, NEW ZEALAND
2. AGRES INVERMAY AGR CTR, MOSGIEL, NEW ZEALAND
3. UNIV MELBOURNE, CTR ANIM BIOTECHNOL, MELBOURNE, VIC AUSTRALIA
4. USDA, MEAT ANIM RES CTR, CLAY CTR, NE 68933 USA
5. INRA, GRP SANGUINS LAB, JOUY EN JOSAS, FRANCE
6. RUHR UNIV BOCHUM, W-4630 BOCHUM, GERMANY
7. VICTORIAN INST ANIM SCI, MELBOURNE, VIC AUSTRALIA
8. CSIRO, MCMASTER LAB, GLEBE, NSW AUSTRALIA
9. UNIV GEORGIA, COLL VET MED, ATHENS, GA 30602 USA |
| Publisher: GENETICS, 428 EAST PRESTON ST, BALTIMORE, MD 21202 |
| Subject Category: Genetics & Heredity |
| IDS Number: RA366 |
| ISSN: 0016-6731 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |