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CRYOPRESERVATION OF HUMAN EMBRYOS AND OOCYTES
Author(s): TUCKER MJ, MORTON PC, SWEITZER CL, WRIGHT G
Source: CURRENT OPINION IN OBSTETRICS & GYNECOLOGY    Volume: 7    Issue: 3    Pages: 188-192    Published: JUN 1995  
Times Cited: 11     References: 0     
Abstract: Human embryo cryopreservation is now a fully established adjunct to assisted reproduction, with thawed embryos implanting at a rate approaching that of fresh embryos. As with fresh embryos, the quality of frozen-thawed embryos is affected by patient age at the time of oocyte retrieval, and by culture conditions. Ovarian stimulation incorporating gonadotropin-releasing hormone analogs does not appear to be detrimental to cryopreservation success, and natural or artificial thaw cycles seem equally effective. Successful cryopreservation seems feasible for one- to eight-cell embryos and blastocysts using a variety of protocols. Selection criteria for embryos to be frozen can vary, and embryo quality has the most significant impact on post-cryopreservation viability. Unfertilized oocyte cryopreservation is coming closer to routine clinical application.
Document Type: Article
Language: English
Reprint Address: TUCKER, MJ (reprint author), REPROD BIOL ASSOCIATES, 5505 PEACHTREE DUNWOODY RD, SUITE 400, ATLANTA, GA 30342 USA
Publisher: CURRENT SCIENCE, 400 MARKET STREET,SUITE 750 ATTN:SARAH WHEALEN/SUB MGR, PHILADELPHIA, PA 19106
Subject Category: Obstetrics & Gynecology
IDS Number: RC113
ISSN: 1040-872X
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