| | |  | | | | Record from Web of Science® | | | | | | |
| FUNCTIONAL DOMAINS OF THE GONADOTROPIN-RELEASING-HORMONE RECEPTOR |
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| Author(s): SEALFON SC, MILLAR RP |
| Source: CELLULAR AND MOLECULAR NEUROBIOLOGY Volume: 15 Issue: 1 Pages: 25-42 Published: FEB 1995 |
| Times Cited: 27 References: 101 |
| Abstract: 1. The cloning of the mammalian gonadotropin-releasing hormone receptor sets the stage for rapid progress in understanding the structure of the receptor, its interaction with ligand, and its mechanisms of activation. 2. The receptor is a 327 to 328-amino acid seven-transmembrane domain G protein-coupled receptor.
3. Recent site-direct mutagenesis studies have provided considerable insight into glycosylation of the receptor, the arrangement of the helices, and the ligand binding domains.
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| Document Type: Review |
| Language: English |
| Reprint Address: SEALFON, SC (reprint author), CUNY MT SINAI SCH MED, FISHBERG RES CTR NEUROBIOL, BOX 1065, 1 GUSTAVE L LEVY PL, NEW YORK, NY 10029 USA |
Addresses:
1. CUNY MT SINAI SCH MED, DEPT NEUROL, NEW YORK, NY 10029 USA
2. UNIV CAPE TOWN, SCH MED, DEPT CHEM PATHOL, MRC, REGULATORY PEPTIDES RES UNIT, CAPE TOWN 7925, SOUTH AFRICA |
| Publisher: PLENUM PUBL CORP, 233 SPRING ST, NEW YORK, NY 10013 |
| Subject Category: Cell Biology; Neurosciences |
| IDS Number: RD929 |
| ISSN: 0272-4340 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |