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| THE SYNAPTIC VESICLE CYCLE - A CASCADE OF PROTEIN-PROTEIN INTERACTIONS |
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| Author(s): SUDHOF TC |
| Source: NATURE Volume: 375 Issue: 6533 Pages: 645-653 Published: JUN 22 1995 |
| Times Cited: 1,539 References: 119 |
| Abstract: The synaptic vesicle cycle at the nerve terminal consists of vesicle exocytosis with neurotransmitter release, endocytosis of empty vesicles, and regeneration of fresh vesicles. Of all cellular transport pathways, the synaptic vesicle cycle is the fastest and the most tightly regulated. A convergence of results now allows formulation of molecular models for key steps of the cycle. These developments may form the basis for a mechanistic understanding of higher neural function. |
| Document Type: Review |
| Language: English |
| Reprint Address: SUDHOF, TC (reprint author), UNIV TEXAS, HLTH SCI CTR, SW MED SCH, DEPT MOLEC GENET, DALLAS, TX 75235 USA |
Addresses:
1. UNIV TEXAS, HLTH SCI CTR, SW MED SCH, HOWARD HUGHES MED INST, DALLAS, TX 75235 USA |
| Publisher: MACMILLAN MAGAZINES LTD, 4 LITTLE ESSEX STREET, LONDON, ENGLAND WC2R 3LF |
| Subject Category: Multidisciplinary Sciences |
| IDS Number: RE576 |
| ISSN: 0028-0836 |
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| |  |  |  |  | | | | Record from Web of Science® | |  |  | | | | | | |