| | |  | | | | Record from Web of Science® | |  |  | | |  |
| TH1 AND TH2 SUBSETS - PARADIGMS LOST |
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| Author(s): KELSO A |
| Source: IMMUNOLOGY TODAY Volume: 16 Issue: 8 Pages: 374-379 Published: AUG 1995 |
| Times Cited: 403 References: 41 |
| Abstract: The T helper 1 (Th1)/Th2 model has provided a valuable framework to investigate and explain many immune reactions and now pervades current thinking on the regulatory role of T cells. However, individual T cells and clones display remarkable diversity in their cytokine profiles, collectively forming a continuous spectrum in which Th1 and Th2 cells may be only two of-the possible extreme phenotypes. For these reasons, Anne Kelso argues that cytokine-producing T cells cannot be classified into discrete subsets. |
| Document Type: Article |
| Language: English |
| Reprint Address: KELSO, A (reprint author), QUEENSLAND INST MED RES, TRANSPLANTAT BIOL UNIT, BRISBANE, QLD 4029 AUSTRALIA |
| Publisher: ELSEVIER SCI LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, OXON, ENGLAND OX5 1GB |
| Subject Category: Immunology |
| IDS Number: RM704 |
| ISSN: 0167-5699 |
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| |  |  |  |  | | | | Record from Web of Science® | |  |  | | | | | | |