| | |  | | | | Record from Web of Science® | | | | | | |
| STRUCTURE AT 2.8-ANGSTROM RESOLUTION OF CYTOCHROME-C-OXIDASE FROM PARACOCCUS-DENITRIFICANS |
|
|
| Author(s): IWATA S, OSTERMEIER C, LUDWIG B, MICHEL H |
| Source: NATURE Volume: 376 Issue: 6542 Pages: 660-669 Published: AUG 24 1995 |
| Times Cited: 1,464 References: 46 |
| Abstract: The crystal structure at 2.8 Angstrom resolution of the four protein subunits containing cytochrome c oxidase from the soil bacterium Paracoccus denitrificans, complexed with an antibody F-v fragment, is described. Subunit I contains 12 membrane-spanning, primarily helical segments and binds haem a and the haem a(3)-copper B binuclear centre where molecular oxygen Is reduced to water. Two proton transfer pathways, one for protons consumed in water formation and one for 'proton pumping', could be identified. Mechanisms for proton pumping are discussed. |
| Document Type: Article |
| Language: English |
Addresses:
1. MAX PLANCK INST BIOPHYS, D-60528 FRANKFURT, GERMANY
2. UNIV FRANKFURT, BIOZENTRUM, INST BIOCHEM, D-60439 FRANKFURT, GERMANY |
| Publisher: MACMILLAN MAGAZINES LTD, 4 LITTLE ESSEX STREET, LONDON, ENGLAND WC2R 3LF |
| Subject Category: Multidisciplinary Sciences |
| IDS Number: RQ672 |
| ISSN: 0028-0836 |
|
| | | | | | | | | Record from Web of Science® | | | | | | | | | |