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| EPR PERSISTENCE MEASUREMENTS OF UV-INDUCED MELANIN FREE-RADICALS IN WHOLE SKIN |
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| Author(s): COLLINS B, POEHLER TO, BRYDEN WA |
| Source: PHOTOCHEMISTRY AND PHOTOBIOLOGY Volume: 62 Issue: 3 Pages: 557-560 Published: SEP 1995 |
| Times Cited: 10 References: 10 |
| Abstract: Electron paramagnetic resonance is used to detect the formation of free radicals caused by exposure to ultraviolet radiation in chemically untreated rabbit skin. A fast jump in EPR signal level, occurring over a few seconds, is observed immediately after a skin sample is exposed to UV. This is followed by a slower increase toward an elevated steady-state signal over a period of hours as the skin is continuously exposed to a UV light source. Upon cessation of UV light exposure, EPR signal levels undergo an abrupt drop followed by a slower decay toward natural levels. Elevated free radical concentrations following UV exposure are found to persist for several hours in whole skin. These results are consistent with time-resolved EPR measurements of photoinduced radicals in various natural melanins. |
| Document Type: Article |
| Language: English |
Addresses:
1. JOHNS HOPKINS UNIV, APPL PHYS LAB, LAUREL, MD 20723 USA
2. JOHNS HOPKINS UNIV, DEPT MAT SCI & ENGN, BALTIMORE, MD 21218 USA |
| Publisher: AMER SOC PHOTOBIOLOGY, BIOTECH PARK, 1021 15TH ST, SUITE 9, AUGUSTA, GA 30901-3158 |
| Subject Category: Biochemistry & Molecular Biology; Biophysics |
| IDS Number: RU156 |
| ISSN: 0031-8655 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |