| GENETIC DISSECTION OF COMPLEX TRAITS - GUIDELINES FOR INTERPRETING AND REPORTING LINKAGE RESULTS |
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| Author(s): LANDER E, KRUGLYAK L |
| Source: NATURE GENETICS Volume: 11 Issue: 3 Pages: 241-247 Published: NOV 1995 |
| Times Cited: 3,419 References: 38 |
| Abstract: Genetic studies are under way for many complex traits, spurred by the recent feasibility of whole genome scans. Clear guidelines for the interpretation of linkage results are needed to avoid a flood of false positive claims. At the same time, an overly cautious approach runs the risk of causing true hints of linkage to be missed. We address this problem by proposing specific standards designed to maintain rigor while also promoting communication. |
| Document Type: Article |
| Language: English |
| Reprint Address: LANDER, E (reprint author), WHITEHEAD INST BIOMED RES, 9 CAMBRIDGE CTR, CAMBRIDGE, MA 02142 USA |
Addresses:
1. MIT, DEPT BIOL, CAMBRIDGE, MA 02139 USA |
| Publisher: NATURE PUBLISHING CO, 345 PARK AVE SOUTH, NEW YORK, NY 10010-1707 |
| Subject Category: Genetics & Heredity |
| IDS Number: TC639 |
| ISSN: 1061-4036 |