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THE CHIP28 WATER CHANNEL VISUALIZED IN ICE BY ELECTRON CRYSTALLOGRAPHY
Author(s): MITRA AK, VANHOEK AN, WIENER MC, VERKMAN AS, YEAGER M
Source: NATURE STRUCTURAL BIOLOGY    Volume: 2    Issue: 9    Pages: 726-729    Published: SEP 1995  
Times Cited: 68     References: 34     
Abstract: Electron crystallography of frozen-hydrated two-dimensional crystals of deglycosylated human erythrocyte CHIP28 reveals an aqueous vestibule in each monomer leading to the water-selective channel that is enclosed by multiple transmembrane alpha-helices.
Document Type: Letter
Language: English
Reprint Address: MITRA, AK (reprint author), SCRIPPS RES INST, DEPT CELL BIOL, 10666 N TORREY PINES RD, LA JOLLA, CA 92037 USA
Addresses:
1. UNIV CALIF SAN FRANCISCO, CARDIOVASC RES INST, DEPT MED, SAN FRANCISCO, CA 94143 USA
2. UNIV CALIF SAN FRANCISCO, CARDIOVASC RES INST, DEPT PHYSIOL, SAN FRANCISCO, CA 94143 USA
3. UNIV CALIF SAN FRANCISCO, DEPT BIOPHYS & BIOCHEM, SAN FRANCISCO, CA 94143 USA
4. SCRIPPS CLIN & RES FDN, DIV CARDIOVASC DIS, LA JOLLA, CA 92037 USA
Publisher: NATURE PUBLISHING CO, 345 PARK AVE SOUTH, NEW YORK, NY 10010-1707
Subject Category: Biochemistry & Molecular Biology; Biophysics; Cell Biology
IDS Number: TD552
ISSN: 1072-8368
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