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| DEBILITATING SILICONE GRANULOMA OF THE PENIS AND SCROTUM |
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| Author(s): WASSERMANN RJ, GREENWALD DP |
| Source: ANNALS OF PLASTIC SURGERY Volume: 35 Issue: 5 Pages: 505-509 Published: NOV 1995 |
| Times Cited: 15 References: 37 |
| Abstract: The restoration and improvement of body contour have intrigued surgeons for over 100 years, generating much interest in the subcutaneous/intradermal injection of highly viscous fluids, The local complications of liquid silicone injection have been well documented over the past 30 years. Although Dow-Coming has not made medical-grade liquid silicone available for use in humans without an approved research application since 1966, practitioners, both licensed and unlicensed, have administered these injections worldwide for a variety of indications throughout the body. There is little or no information concerning the adulteration of these injectates. To date, there have been four case reports of penile injections-the indications being evenly split between the treatment of impotence/sexual inadequacy and augmentation, The most recent description was published in 1982. We present a case of debilitating silicone granuloma of the penis and scrotum secondary to large-volume injections into the corpora cavernosae and penile soft tissues administered in Belgium 14 years prior to presentation. The development of a silicone foreign body reaction, massive edema, and subsequent impotence lends itself to a clinical diagnosis and aggressive treatment with wide local excision and appropriate soft-tissue coverage. The metabolic fate of silicone in vivo remains inadequately characterized and a fertile area for research as new methods involving nuclear magnetic resonance spectroscopy have been devised to identify silicone and highly coordinated silicone complexes. |
| Document Type: Article |
| Language: English |
Addresses:
1. UNIV S FLORIDA, DIV PLAST SURG, TAMPA, FL USA |
| Publisher: LITTLE BROWN CO, 34 BEACON STREET, BOSTON, MA 02108-1493 |
| Subject Category: Surgery |
| IDS Number: TF257 |
| ISSN: 0148-7043 |
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