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Cytokines in implantation
Author(s): Chard T
Source: HUMAN REPRODUCTION UPDATE    Volume: 1    Issue: 4    Pages: 385-396    Published: JUL 1995  
Times Cited: 75     References: 134     
Abstract: The process of implantation in the human involves 'invasion' of the maternal endometrium by the trophoblast surrounding the developing blastocyst, in response to which there is a cellular reaction in the endometrium. The overall situation has some features analogous to invasion by a tumour and some which are more characteristic of an inflammatory response, In addition, and also in common with cancer and inflammation, there is a release of biologically active molecules, including cytokines, at and around the implantation site. It is believed that these cytokines may play an important role in the successful establishment of the pregnancy; the evidence for this belief is examined in this review.
Document Type: Review
Language: English
Reprint Address: Chard, T (reprint author), UNIV LONDON ST BARTHOLOMEWS HOSP & MED COLL, DEPT REPROD PHYSIOL, LONDON EC1A 7BE, ENGLAND
Addresses:
1. UNIV LONDON ST BARTHOLOMEWS HOSP & MED COLL, DEPT OBSTET & GYNAECOL, LONDON EC1A 7BE, ENGLAND
2. LONDON HOSP, COLL MED, LONDON E1 1BB, ENGLAND
Publisher: OXFORD UNIV PRESS UNITED KINGDOM, WALTON ST JOURNALS DEPT, OXFORD, ENGLAND OX2 6DP
Subject Category: Obstetrics & Gynecology; Reproductive Biology
IDS Number: TT798
ISSN: 1355-4786
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