| | |  | | | | Record from Web of Science® | | | | | | |
| Toward an understanding of the correlates of protective immunity to HIV infection |
|
|
| Author(s): Haynes BF, Pantaleo G, Fauci AS |
| Source: SCIENCE Volume: 271 Issue: 5247 Pages: 324-328 Published: JAN 19 1996 |
| Times Cited: 313 References: 194 |
| Abstract: Considerable progress has been made recently in understanding the genetic, immunologic, and virologic factors in human immunodeficiency virus (HIV)-infected individuals who either rapidly progress or do not progress to acquired immunodeficiency syndrome (AIDS). In addition, detection of HIV-specific immune responses in HIV-negative individuals who have been exposed to the virus multiple times suggests that natural immune responses to HIV may be protective in rare individuals. Understanding the correlates of protective immunity to HIV infection is critical to efforts to develop preventive HIV vaccines as well as to determine the feasibility of treating HIV infection by boosting immunity to HIV. |
| Document Type: Review |
| Language: English |
Addresses:
1. DUKE UNIV, MED CTR, DEPT MED, DIV RHEUMATOL ALLERGY & IMMUNOL, DUKE CTR AIDS RES, DURHAM, NC 27710 USA
2. NIAID, IMMUNOREGULAT LAB, BETHESDA, MD 20892 USA |
| Publisher: AMER ASSOC ADVANCEMENT SCIENCE, 1200 NEW YORK AVE, NW, WASHINGTON, DC 20005 |
| Subject Category: Multidisciplinary Sciences |
| IDS Number: TQ528 |
| ISSN: 0036-8075 |
|
| | | | | | | | | Record from Web of Science® | | | | | | | | | |