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Methods for microelectrode-guided posteroventral pallidotomy
Author(s): Lozano A, Hutchison W, Kiss Z, Tasker R, Davis K, Dostrovsky J
Source: JOURNAL OF NEUROSURGERY    Volume: 84    Issue: 2    Pages: 194-202    Published: FEB 1996  
Times Cited: 262     References: 34     
Abstract: Methods for localizing the posteroventral globus pallidus internus are described. The authors' techniques include the use of microelectrodes to record single-unit activity and to microstimulate in human pallidum and its surrounding structures. This technique allows a precise determination of the locations of characteristic cell types in sequential trajectories through the external and internal segments of the pallidum. The location of the optic tract can be determined from microstimulation-evoked visual sensations and recordings of flash-evoked potentials. In addition, microstimulation-evoked motor and sensory responses allow the internal capsule to be identified. The data collected using this technique are an important adjunct to selecting optimum sites to place electrocoagulation lesions for stereotactic posteroventral pallidotomy for refractory Parkinson's disease.
Document Type: Article
Language: English
Addresses:
1. UNIV TORONTO, DEPT PHYSIOL, FAC MED, TORONTO, ON M5S 1A8 CANADA
2. TORONTO HOSP, WESTERN DIV, DIV NEUROSURG, TORONTO, ON M5T 2S8 CANADA
3. TORONTO HOSP, WESTERN DIV, PLAYFAIR NEUROSCI UNIT, TORONTO, ON M5T 2S8 CANADA
Publisher: AMER ASSOC NEUROLOGICAL SURGEONS, UNIV VIRGINIA, 1224 WEST MAIN ST, STE 450, CHARLOTTESVILLE, VA 22903
Subject Category: Clinical Neurology; Surgery
IDS Number: TR895
ISSN: 0022-3085
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