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Who's competent and when: Regulation of natural genetic competence in bacteria
Author(s): Solomon JM, Grossman AD
Source: TRENDS IN GENETICS    Volume: 12    Issue: 4    Pages: 150-155    Published: APR 1996  
Times Cited: 84     References: 59     
Abstract: Natural genetic competence, the ability of cells to bind to and to take up exogenous DNA, is widespread among bacteria and might be an important mechanism for the horizontal transfer of genes. Competent cells express specialized proteins that assemble into a DNA-uptake complex. In many organisms, the development of competence and expression of the uptake machinery is regulated in response to cell-cell signaling and/or nutritional conditions. Exciting new progress has been made in characterizing the signals and pathways that regulate the development of competence.
Document Type: Review
Language: English
Reprint Address: Solomon, JM (reprint author), MIT, DEPT BIOL, BLDG 68-530, CAMBRIDGE, MA 02139 USA
Publisher: ELSEVIER SCI LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, OXON, ENGLAND OX5 1GB
Subject Category: Genetics & Heredity
IDS Number: UC599
ISSN: 0168-9525
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