| | |  | | | | Record from Web of Science® | |  |  | | |  |
| Who's competent and when: Regulation of natural genetic competence in bacteria |
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| Author(s): Solomon JM, Grossman AD |
| Source: TRENDS IN GENETICS Volume: 12 Issue: 4 Pages: 150-155 Published: APR 1996 |
| Times Cited: 84 References: 59 |
| Abstract: Natural genetic competence, the ability of cells to bind to and to take up exogenous DNA, is widespread among bacteria and might be an important mechanism for the horizontal transfer of genes. Competent cells express specialized proteins that assemble into a DNA-uptake complex. In many organisms, the development of competence and expression of the uptake machinery is regulated in response to cell-cell signaling and/or nutritional conditions. Exciting new progress has been made in characterizing the signals and pathways that regulate the development of competence. |
| Document Type: Review |
| Language: English |
| Reprint Address: Solomon, JM (reprint author), MIT, DEPT BIOL, BLDG 68-530, CAMBRIDGE, MA 02139 USA |
| Publisher: ELSEVIER SCI LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, OXON, ENGLAND OX5 1GB |
| Subject Category: Genetics & Heredity |
| IDS Number: UC599 |
| ISSN: 0168-9525 |
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| |  |  |  |  | | | | Record from Web of Science® | |  |  | | | | | | |